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How to Make Sure You Travel with Medication Legally

Traveling with medication — even prescription drugs — isn’t as simple as packing it. Here’s how to stay on the right side of the law, anywhere you go.

By Tanya Mohn

Travelers often pack medications when they go abroad, but some popular prescription and over-the-counter ones Americans use for things like pain relief, better sleep, allergies and even the common cold are illegal in some countries.

The United Arab Emirates and Japan, for example, are among the most restrictive nations, but many ban or restrict importing narcotics, sedatives, amphetamines and other common over-the-counter medications.

Most travelers won’t run into problems for carrying small amounts for personal use, said Katherine L. Harmon, who oversees health analysis for iJET International , a travel risk management company. But noncompliance can result in confiscation,(which could, in turn, have severe medical consequences), deportation, jail time, and even the death penalty. “Does it happen a lot? No. Could it? Yes,” Ms. Harmon said. “Consumers need to understand this and how it might adversely impact them before they book that awesome trip to an exotic location.”

She shared a few tips to keep you on the right side of the law, whatever you take and wherever you roam.

Laws vary by country and there is no central, up-to date repository, so Ms. Harmon suggests consulting your physician, travel medical insurance company, or local pharmacist four to six weeks before traveling. “When you inquire about your shots, ask about medications. Odds are they may not know off the top of their head, but they have the resources to find out.”

She also suggests checking with the embassy of your destination country. The State Department website lists foreign embassies in the United States, and their contact information. It also lists insurance providers that offer overseas health coverage. Comparison websites Insure My Trip and SquareMouth can help assess those insurance plans, if they’re necessary.

Label and Pack Your Medication Properly

Carry all of your medication — even vitamins and supplements — in their original, clearly marked containers or packaging in a clear plastic bag in carry on luggage. Make sure the name on the prescription, the medicine container and your passport (or one for the recepient of the medication) all match. If you lost the product information insert, ask the pharmacist to print a new one for you.

Also, check the Transportation Security Administration’s website for up-to-date rules and regulations on packing and carrying your medication when you depart. The standard rules for liquid carry-ons don’t apply to medications in liquid or gel form, but you need to inform the T.S.A. when you pass through security so they don’t confiscate it .

Obtain and Carry Necessary Documentation

Keep copies of your original prescriptions, if you can . Better yet, obtain a letter on official letterhead from your physician that lists the medicines you need and why they were prescribed. Ideally, you would get this translated to the language of your destination country, so it’s easy to read.

For some medication and specialized equipment used to administer them, some countries require documents to be submitted to government officials well in advance of your arrival. Ms. Harmon, for example, was questioned at the Singapore airport once for entering with an EpiPen, but she had prior authorization allowing its transport.

Know the Names and Amounts of Active Ingredients

The documentation you carry should also indicate the generic and chemical names of the active ingredients, which determines permissibility, not brand names.

For example, the active ingredient in Benadryl, diphenhydramine, is banned in Zambia in over-the counter products. In Japan, it is allowed only if the amount in a tablet or injection is limited. However, a typical 25 milligram tablet of Tylenol PM in the United States exceeds the 10 milligram maximum amount in a tablet you can bring into Japan. Some countries restrict the overall total amount of an active ingredient an individual traveler can legally import, which may impact longer stays.

Reduce or Substitute Medication

In countries where a medication is allowed, but its amount is capped, reducing your dosage or switching to another available medication is the best way to stay compliant. Allow enough time beforehand to ensure the smaller dose or new medicine works effectively, and consider making the switch before your trip to give yourself time to adjust.

Some medications can be used for several diagnoses. Hormones used for birth control may also be used to treat excessive menstrual bleeding, Ms. Harmon said. “Doctors need to get creative sometimes. Substitutions can allow authorities to accept the drug as a medical need rather than going against the country’s religious or moral code.”

Reassess Your Travel Plans

Parents with a child doing well on Adderall for attention deficit hyperactivity disorder who prefer not to make adjustments on the fly, or a student with bipolar disorder may want to consider vacation or study abroad locations where the medications they rely on for mental health are not banned or restricted.

“Viewpoints on treatment and diagnoses can vary widely,” Ms. Harmon said. “Western Europe and North America understand that brain chemistry is often at the root of these problems. But some countries, like Russia, do not consider mental health challenges as medical problems and often treat them criminally.”

Anti-Anxiety Medication and Flying

Attempts to medicate flight anxiety away are likely to backfire..

Posted July 15, 2014 | Reviewed by Jessica Schrader

• What Is Anxiety?
• Find a therapist to overcome anxiety

Anti- anxiety medication to reduce flight anxiety backfires. The temporary—and generally inadequate—relief gained comes with a high long-term cost. Anti-anxiety medications prevent anxious fliers from getting used to flying. They increase the anxious flier's sensitivity to the plane’s noises and motions. They impact the person’s memory and ability to learn. They cause psychomotor impairment. And, they are addictive.

According to research at the Stanford University School of Medicine, though the person taking anti-anxiety medication may feel more relaxed psychologically, there is increased arousal physiologically. “Alprazolam increases physiological activation under acute stress conditions and hinders therapeutic effects of exposure in flying phobia .”

In this research study, 28 anxious fliers took two flights. On the first flight, half received alprazolam (generic Xanax) and half received a placebo .

Those taking alprazolam reported significantly reduced levels of anxiety compared with those taking a placebo during the first flight. However, their heart rate (114 bpm) and breathing rate (22.7 breaths/min) were much higher than in the group that had taken a placebo.

On a second flight a week later without medication, 71 percent of those who had taken alprazolam on the first flight had significantly increased anxiety, an increased heart rate (123 bpm), a desire to leave the plane, and panic. Commenting on this research in an article in Clinical Psychiatry News, Shanna Treworgy, Psy.D., of the Dartmouth Geisel Medical School, said that though there may be reduced anxiety in the moment, benzodiazepines cause increased long-term anxiety reactions. This, she reported, has been "documented in both animal and human studies.”

An article in Clinical Psychiatry News says, "Widespread long-term use of benzodiazepines for anxiety remains a reality, despite guidelines that recommend against the practice.” Dominic Candido, who teaches psychiatry at the Dartmouth Geisel School of Medicine, says the use of benzodiazepines "significantly diminishes the effects" of treatment for anxiety. Short-term relief is, he says, "often at long-term detriment to the patient.”

Taken as prescribed, anti-anxiety medications do not adequately relieve flight anxiety. During flight, when the prescribed dose fails to provide relief, an anxious flier—perhaps in a state of panic—is likely to take more and, perhaps, to combine it with alcohol . Combining anti-anxiety medication with alcohol is unsafe. A news article about the excessive in-flight use of Xanax by actress Winona Ryder is at this link .

On the other hand, those who had taken a placebo on the first flight showed significant improvement. Having gained some degree of desensitization during the first flight, they now reported less anxiety.

In a New York Times article on flight phobia, psychiatrist Richard A. Friedman, M.D. wrote, "If you think you can outsmart your phobia with anti-anxiety medications like Valium and Klonopin, forget about it; they might numb you during an acute panic attack, but they will not erase your phobia. In fact, they could get in the way of therapy because they impede new learning, which is the essence of curing phobias. To kick a travel phobia, you have to fight fire with fire; you have to tolerate some anxiety to get rid of it. No shortcuts.”

Captain Tom Bunn, LCSW , is an airline pilot and author who has dedicated 30 years to the development of effective methods for treating flight phobia.

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UponArriving

TSA Medication Rules for Flying on Planes [2024]

Traveling through airport security can already be a pretty nerve-racking experience.

But when you are also worried about getting your necessary medical items through security and onto a plane for a flight, it can be even more anxiety inducing. Luckily, there are some pretty lenient TSA rules and guidelines when it comes to flying with your medication.

In this article, I will tell you everything you need to know about TSA medication rules and flying on a plane with medication . I’ll go over the rules for things like prescription medications, pills and liquid medication and other situations like over the counter (OTC) drugs. 

Table of Contents

What are the TSA rules for flying with medication on a plane?

TSA will generally allow you to travel with your medication but there are some restrictions that you need to be aware of, especially if bringing medical liquids. Below, I will go through some of the most common restrictions that might apply to you and tell you how you can go about them when flying with medication. 

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Does TSA have a limit on the amount of medication I can bring on a plane?

TSA does not have a limit on the amount of medication that you can bring on a plane whenever the medication is in solid form, such as pills . So if you have a need to travel with multiple bottles of pills then you should not be limited to a certain amounts of pills or bottles. 

If you have an outrageous amount of medication on you then you might be subject to additional screening. However, in many cases as long as they can x-ray your medication they will not require you to undergo additional screening.

If you do not want your medication exposed to the x-ray machine then just let the TSA agent knows this and they will allow you to go through a different type of screening (note that this could take more time and require you to open up all of your bottles).

Note: Medical Nitroglycerin medicines are allowed.

Related: Can TSA Ask About Your Medical Condition?

What are the TSA rules for traveling with liquid medication on a plane?

If you are not aware, TSA has a rule that forbids you from bringing in liquids than can’t fit in 3.4 ounce containers. Also, these containers must fit into a quart size bag (typically a clear Ziploc bag).

This is known as the “TSA 3-1-1 rule” and you will be required to remove the bag from your carry-on unless you have TSA Pre-Check (which I highly recommend). 

TSA does not enforce the liquids rule for medically required liquids (and gels and aerosols) . They also don’t require you to put your medically necessary liquids into a liquids bag.

However, they do have some limitations on liquid medication.

They require you to only bring “reasonable quantities” and state that the liquids rule exemption only allows certain items to be carried on the aircraft when the item is declared and it is:

• Required during your flight and/or at your travel destination;
• Not available at the airport in the sterile area (after the screening checkpoint) and/or;
• Not available at your travel destination.

Reasonable quantities for your trip

When you are bringing your liquid medications through security the TSA 3-1-1 rule does not apply. Instead, TSA will allow you to bring in “reasonable quantities for you trip.” This is a subjective definition so there is going to be room for agent discretion. 

Therefore, try not to go too far with your liquid medications if you think that you might be bringing in an unreasonable amount. It is a very good idea to have a clear stated purpose for why you need that quantity of liquid medication. And it might even be a better idea if you have a signed doctor’s note explaining why you need that much medication.

It could probably help your cause if you can explain your dosage requirements in relation to the quantity of medication you are bringing. For example, if you require 10g of medication per day and you are bringing 100g with you on a ten day trip, that makes total sense.

But if you require 10g of the medication per day and you are bringing 3,000g with you for a weekend trip that could be a different story….

At some point TSA added more clarity to this rule when they stated that the medication would need to not be available at the airport in the sterile area (after the screening checkpoint) and/or not available at your travel destination.

I don’t really like this rule because essentially a TSA agent could force you to throw out a large bottle of NyQuil just because it would be available at an outrageous price within the airport. Also, sometimes it’s difficult to know whether or not something will be available at your destination so it is just smart thinking to bring it with you. Nevertheless, those are the rules.

Notify the agents 

TSA also states that you should notify the TSA agent about your liquid medication before you go through security screening.

Personally, I have flown with liquid medication many times before and have never notified TSA about it nor have they given me any push back (there’s a prescription on the medication bottle).

Even though that is how I have done it in the past, I would recommend disclosing your medication just to make things easier. This is especially the case if you’re traveling with accessories associated with your liquid medication such as freezer packs, IV bags, pumps, and syringes.

If TSA does notice your liquids or you tell them about them, the medically required liquids will be subjected to additional screening that could include being asked to open the container. They might pour the substance into another container, test out a small sample of the medication, or swab it for explosives .

So just be prepared to pop the top if you are asked to. 

Note: You will not have to put your liquid medications into a Ziploc bag.

Related: Can You Bring CBD on a Plane? (TSA Rules)

How to pack medication for a flight in a carry-on or checked bag

TSA will allow you to bring your medication onto a plane via carry-on or checked baggage.

Obviously, you will not have access to your checked baggage when you are flying in the plane so if you are in doubt about whether or not you might need access to your medication, then I highly recommend that you pack it in your carry-on. 

Plus, remember if your checked bag containing your meds gets lost your medication is also lost.

If you bring your medication as a carry-on you should not be required to show or declare that you are bringing medication, unless you are bringing liquid medication or certain other types of medical instruments like syringes.

(Some travelers inform the TSA agents about all medications they are bringing but that does not always seem to be required in my experience.)

When packing pills or medication I would try to keep them organized in a clear plastic bag just to make things easy at all times.

Try to pack that bag in an easily accessible area within your carry-on so that you can quickly retrieve it if you need to declare or allow inspection for any of your medications.

Also, it’s a good idea for your medications to be labeled to facilitate the security process. (Labeling your meds is not required but it is recommended by TSA.)

When packed in a carry-on and going through a security checkpoint your medication can undergo a visual or X-ray screening (you can choose).

Does TSA require pills to be in a prescription bottle ?

Believe it or not TSA does not require your pills to be in a prescription bottle or to show them a copy of your prescription. The catch is that states have different laws regarding how you can legally travel with prescription items.

Some states might require you to carry your pills and a bottle with a prescription and therefore it is always a good idea to keep your pills in a bottle with a prescription label if possible or at least keep the prescription with you if you are using a pill container/organizer. 

Also, many countries have very strict rules on prescription medication so be sure to keep up with the latest laws before departing the country. Some might require you to submit a letter from a physician and some countries such as those in the Middle East have very strict laws regarding bringing in certain types of medications.

It is not very difficult to find stories about US tourists getting locked up abroad in prison for bringing medications through the airport.   Read more about traveling internationally with medication here.

One interesting thing about prescriptions is that if you forget your ID you can actually use your prescription labels to help verify your identity.

Tip: Ask your pharmacist for extra containers with your name and the medication information on them if you want to carry smaller amounts of drugs with you.

What are the TSA rules for flying on a plane with injectable medication?

You are allowed to travel with injectable medication on a plane. You may also bring unused syringes  when they are accompanied by injectable medication. You must declare these items to security officers at the checkpoint for inspection. TSA also recommends, but does not require, that your medications be labeled so it’s a good idea to go with their recommendation. 

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What if I need to keep my medication refrigerated when flying? 

If you need to keep your medication refrigerated you can use “ice packs, freezer packs, gel packs, and other accessories” to keep your medication cool. You will need to present these at the screening checkpoint in a frozen or partially-frozen state.

It would be a good idea to do a “test run” to see how long your packs can stay refrigerated, especially if you are going to be dealing with a long layover or flight. Some airplanes may have refrigeration but I would not count on that.

Does TSA allow over the counter medication on a plane?

TSA will allow you to bring over the counter medication on a plane, which means you’ll be fine to bring along things like: Tylenol, Advil, Aleve, ibuprofen, etc. Just remember that the rules pertaining to liquids will apply to OTC drugs unless they are medically necessary.

I always advise people to put their medication in a clear plastic bag just to make things easier when making your way through airport security.

Related: Does TSA Check For Arrest Warrants?

What about flying with other items?

If you have questions about bringing other types of items through TSA airport security screening (like food or alcohol), make sure to check out the articles below: 

• Bringing food through an airport 
• Bringing alcohol through an airport
• Bringing gun cases through an airport 

Yes, prescription medication is allowed on planes.

No, your medication does not have to be in the original bottle. However, it’s usually a good idea to have a prescription on hand just in case you’re questioned about the medication.

It’s best to be upfront about bringing medication through TSA, especially because TSA is pretty flexible about what medications you can bring through and all medication must be screened. If you are trying to sneak illegal drugs through TSA security you could be referred to law enforcement.

Yes, you can bring your pill organizer on a plane with your pills inside.

TSA does not require you to show your prescription so it could be possible to bring someone else’s prescription meds with you on a plane. However, it’s a good idea to make sure you are complying with state laws regarding prescription drugs when traveling. In some cases, it may be illegal to possess controlled substances prescribed to someone else.

Yes, cough syrup will be considered a liquid so you should “declare” it when going through TSA, especially if it is above 3.4 ounces.

Yes, you can bring testosterone gel on a plane. While you may not need your prescription it never hurts to bring it along.

TSA states used syringes are allowed when transported in Sharps disposal container or other similar hard-surface container. Unused syringes are allowed when accompanied by injectable medication. You must declare these items to security officers at the checkpoint for inspection.

As you can probably tell, TSA rules regarding medication are actually pretty lenient. They allow you to bring an unlimited amount of pills and solid drugs and they don’t even require you to show or disclose that you are bringing those drugs through the airport and onto the plane. 

They also will allow you to go above the liquids rule if you are willing to allow them to inspect your drugs if necessary. And they don’t even require you to show your prescription for drugs. Therefore if you are planning to travel through the airport with your medication you may not have as difficult a time as you may have imagined. 

Daniel Gillaspia is the Founder of UponArriving.com and the credit card app, WalletFlo . He is a former attorney turned travel expert covering destinations along with TSA, airline, and hotel policies. Since 2014, his content has been featured in publications such as National Geographic, Smithsonian Magazine, and CNBC. Read my bio .

16 comments

Does the TSA have an official form where a person could list all his/her medication and have it signed by a doctor to insure the traveler is not harassed or blamed for bringing in drugs that are not prescribed?

I’m travelling to Dublin by aeroplane and I take over the counter co codomal painkillers for my back am I allowed these in my luggage

I’m trying to find out if I can put my medication and a seven day pill container and not take the original prescription bottles with me. We will be leaving from Dayton Ohio, stopping in Charlotte North Carolina, and ending up in Texas. I don’t want to do the wrong thing and end up not being able to take any of my medication with me! We are leaving in two days so I’d appreciate a quick answer. Thank you so much.

Chances are you will be fine without the pill bottles. But it is always a good idea to have your prescription on you just in case.

Did you get through the airports okay without the prescription bottles? I am going from Missouri to Maine soon and can’t seem to find any definite information on whether or not I need to carry the original prescription bottles or not.

I take 11 prescriptions daily, so I put my pills in a 8-day travel medication wallet that has small ziplocks for each day. I also get the pharmacy to print out my prescription list for me. I have been doing this for several years and have never been asked about my medication or to show prescriptions. I travel with a cpap and am only asked to unzip the case so they can see the cpap. This past summer, they did take and test my 8-oz bottle of hand sanitizer and gave it back. There was no problem though. I also take a frozen bottle of water without a problem. It may melt slightly, so I drink that and replace the cap.

I’m a nurse traveling to the USA to visit my sister and was wanting to take over Botox with me to inject as mmmmm as her birthday gift. Is this allowed

I will soon travel to Thailand With injectable medications. They need to stay colds too, I will obtain an insulin travel pack and bring it through in my carry on luggage and inform the TSA officers about it ahead of time. I can also do a pre TSA check in? SO they know I am coming with the meds? I will have doctors note, prescription too. The meds need to be kept cold too.

I will be traveling to Ireland next year and have both prescription and over the counter vitamins. Do I need to make a list of these items to present. I wanted to divide them by day since I will be gone for 2 weeks, but if I need to bring the bottles I can.

Hi there, for the vitamins you probably don’t need the bottles but having a list or the labels could help w/a difficult TSA agent.

For the prescription meds, I would also try to bring the prescription. But you should be fine to bring your pills in a pill organizer if that’s what you have.

Hi I have to take can Fexofenadine , and have to wash with Hydromel Cream lotion this only comes in a plastic pump bottle will they let me go through with these.

Can I bring opened bottles of OTC meds and can they be in my carry on or go into my checked bag?

Yes, and they can go in either one.

Can I bring my anxiety medication in my pocket for the plane ride 2 klonpins or 2 Xanax in my pocket through the tsa security?

If going through the full body scanner, you won’t be able to because it will trigger the alarm. Best to keep them in your bag.

can I fly with perscribed gummies?

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What You Should Know About Taking Xanax Before a Flight

A flight can be a very stressful affair with long lines, rushed schedules, security checkpoints, turbulence, and everything else. Long flights may sound scary too especially if you’re a first-timer. If it’s your first flight and traveling alone, you don’t know what to expect. While some people developed a fear of flying due to bad past experiences on a flight.

Many people take Xanax, Valium, or other anxiety medications to deal with pre-flight nerves or to deal with flight anxiety. While these prescription medications may effectively treat anxiety disorders and other mental health conditions, people should only take them under a doctor’s supervision.

Xanax misuse can be extremely dangerous, and you don’t want to have a medical emergency while on air travel. So you need to read this easy guide to learn more about Xanax abuse and find out how to get help if you have a problem.

Table of Contents

• 1 What Is Xanax?
• 2 Is Xanax Addictive?
• 3 Is It Okay To Self-Medicate With Xanax?
• 4 Can Xanax Cure My Anxiety?
• 5.1 Arrive at the Airport Early
• 5.2 Bring Entertainment
• 5.3 Speak to a Doctor About Your Anxiety
• 6 How Much Xanax Should I Take?
• 7 Is Mixing Alcohol and Xanax Dangerous?
• 8 Will I Go Through Withdrawal After Quitting Xanax?
• 9 Is an Addiction Treatment Program Worth It?
• 10 Safeguard Your Health and Future

What Is Xanax?

Xanax is the trade name of alprazolam, a common benzodiazepine . Doctors commonly prescribe Xanax to treat anxiety disorders and panic disorders. With the right dosage and under a doctor’s supervision, Xanax can prevent panic attacks and ease symptoms of anxiety.

Xanax has stronger side effects than most other anxiety drugs, especially the sedation and drowsiness part. Thus, if you haven’t taken an anti-anxiety medication to treat anxiety before, then your doctor will likely try to put you on a drug with fewer side effects before prescribing a benzodiazepine.

Is Xanax Addictive?

Like other benzodiazepines, Xanax has a fairly high risk of addiction. This is why it’s so important to follow your doctor’s instructions when taking this medication. Snorting Xanax, regularly taking more than your prescribed dosage, drinking liquor with Xanax, and mixing it with other drugs can be very dangerous. If you feel the urge to misuse Xanax, then you should talk to your doctor immediately so that they can wean you off the drug and find a safer alternative.

Xanax for Flying

Is It Okay To Self-Medicate With Xanax?

You should not consume Xanax without a prescription for any reason, even if you have a flying phobia. Ii is never okay to take Xanax without medical advice. When a doctor prescribes Xanax, they take the patient’s weight, gender, symptoms, medications, health conditions, and other factors into account to find a safe and effective dosage.

Without a medical professional’s guidance, you could easily overdose on Xanax, exacerbate an undetected medical condition, have a bad drug interaction, or develop an addiction. Taking someone else’s prescription can be incredibly dangerous.

While a dealer or friend may say that they’re giving you a certain dose of Xanax, you have no way to verify that information. Unfortunately, drug dealers and illegal drug manufacturers are very skilled at making counterfeit prescription drugs appear authentic.

In turn, you may think that you’re purchasing Xanax when you’re actually getting something else that the manufacturers could have laced with fentanyl and other deadly adulterants. Self-medicating is very risky, and you don’t want to put your life on the line to treat your anxiety.

With that in mind, if you think that you need Xanax or another prescription drug to treat your anxiety, then you must speak to a doctor and follow their instructions.

Can Xanax Cure My Anxiety?

Xanax treats the symptoms of anxiety, but it is not a complete solution. To stop worrying so much about flying, you need to understand and address the root causes of your anxiety. Your doctor will likely refer you to a mental health specialist to help you develop effective coping mechanisms. Depending on your health and the extent of your symptoms, the doctor may or may not prescribe Xanax or another drug to take in conjunction with psychotherapy.

What Should I Do if I’m Anxious About Flying?

If you have a fear of flying or if it’s your first time going on a flight, there are things you can do to avoid being anxious. You don’t have to resort to anxiety meds right away. On your next flight, try these tips.

Arrive at the Airport Early

The hustle and bustle of going through the security checkpoint, waiting in all sorts of lines, checking in, and sticking to a tight schedule may induce a lot of anxiety. You may panic, feel sweaty, and your heart rate beats so fast.

You can avoid some of that pre-flight tension by arriving at the airport an hour earlier than you normally would. The lines will be shorter, so you’ll get more time to relax and take care of any last-minute issues before your flight.

Bring Entertainment

Knowing that you’re in an aircraft thousands of feet above the ground can be pretty unnerving. To distract yourself from that sense of helplessness, you should bring a book or download your favorite movies, shows, and audiobooks. A good pair of noise-canceling headphones will help you sleep, and soften any loud or sudden noises during your flight.

Speak to a Doctor About Your Anxiety

If you still feel intense anxiety about flying no matter what you try, then you must speak to your doctor as soon as possible. Making it to a physical doctor’s appointment can be inconvenient, but many doctors now offer telemedicine services so that you can access high-quality healthcare from the comfort and convenience of your own home.

When discussing your problems with your doctor, make sure to include as many details as possible. Even if a certain aspect of your experience seems mundane or insignificant, it can give your doctor more insight into your condition, so try to be open and honest about your symptoms and feelings. The intervention for fears and phobias is Exposure Therapy which a therapist can help with.

How Much Xanax Should I Take?

Your doctor is the only person who can determine how much Xanax you should take. If you feel like your current dosage isn’t working, then you should let your doctor know right away. They’ll increase your dosage, put you on another medication, or find some other solution to your problem.

Do not change your dosage without consulting a doctor. Failure to take the prescribed dose at the proper frequency may lead to an overdose, worsen anxiety issues, drug resistance, and other serious problems.

Is Mixing Alcohol and Xanax Dangerous?

Alcohol is one of the worst substances to take with Xanax. Even a single drink, while you’re on Xanax, could lead to severe memory loss, poor coordination, impaired judgment, and respiratory problems.

Drinking heavily and taking Xanax at the same time may result in severe liver damage, brain damage, overdose, coma, and death. Xanax can take up to three days to completely leave your system, so you should not consume alcohol if you’ve taken Xanax within the last few days.

Will I Go Through Withdrawal After Quitting Xanax?

Most individuals who struggle with Xanax addiction begin to experience acute withdrawal symptoms within three days of their last dose. Common symptoms of Xanax withdrawal include anxiety, insomnia, muscle spasms, psychosis, seizures, nausea, light sensitivity, and body aches.

These symptoms will peak within a couple of weeks and persist for up to a month. Heightened anxiety and other psychological symptoms may continue for years after a patient quits Xanax. The first month of Xanax withdrawal is extremely challenging.

Thus, increasing your odds of success and minimizing the chances of experiencing a seizure or psychosis at a dangerous time. You should consider enrolling in a detox program at an addiction recovery facility. Detox centers employ medical staff and therapists to keep patients safe, healthy, and comfortable as they endure the worst withdrawal symptoms.

Is an Addiction Treatment Program Worth It?

Individuals who go through professional addiction treatment programs are more likely to maintain long-term sobriety. In a treatment program, you’ll attend therapy sessions with a qualified addiction professional to address your substance use, anxiety, and other problems.

You’ll also attend group sessions with other individuals who suffer from addiction, and you can participate in a wide range of fun and healthy activities at the treatment center. During the treatment process, you will build the necessary coping strategies to manage your anxiety and avoid abusing drugs for the rest of your life.

An inpatient program will completely remove your access to Xanax and other addictive substances for the duration of your stay. This will greatly increase your odds of making it through the most difficult stage of addiction recovery. No two patients experience addiction or anxiety in the same way, so the therapists at a reputable addiction recovery center won’t treat you with a one-size-fits-all approach.

Instead, they’ll assess your condition and consider your thoughts and feelings as they craft a treatment regimen that works for you. You only live once, so it’s important to do everything in your power to keep your mind and body healthy. An addiction treatment program will give you the right tools for lifelong success, sobriety, and happiness.

Safeguard Your Health and Future

Between the risk of overdose, serious injury, legal trouble, permanent brain damage, organ failure, and psychological harm, misusing Xanax is just not worth the supposed benefits. Quitting Xanax can be challenging, but you don’t have to do it alone. If you want to treat your anxiety and stop abusing Xanax, then you should call or email NJ Addiction Resources as soon as possible to find the best treatment program for your unique needs.

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• Alprazolam (Oral Route)

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Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day.
• Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed.
• Children—Use and dose must be determined by your doctor.
• Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day.
• Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed.
• Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

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10% of travelers have had their medicines confiscated. Here's how you can avoid it.

It’s always a good idea for passengers to keep medicine in their carry-on bag, but even that doesn’t guarantee they’ll get to their final destination with all their prescriptions.

According to a January survey of 1,245 Americans from BuzzRx , a prescription discounting service, one in 10 Americans have had their medicine confiscated while traveling, either by the Transportation Security Administration or by border officers abroad.

“Before traveling, it’s imperative to research the destination, especially if traveling internationally, about what their medication requirements are,” Ricardo Rodriguez, a member of BuzzRx’s data team, told USA TODAY. 

Rodriguez explained that some U.S. medications are not approved in other countries, which could make traveling with them complicated. “Discussing the issue with your provider will probably be the best thing to do.”

Medicine is almost equally likely to be confiscated on domestic trips, with 41% of respondents saying it has happened to them, as on international trips, with  44% of respondents saying they’d experienced it.

Planes carry medical kits. Here's why you may not rely on them in an emergency.

For domestic trips, the TSA recommends keeping your prescriptions in their original, marked containers. TSA regulations allow travelers to bring more than 3.4 ounces, the usual limit for liquids, if their medicine comes in liquid form.

Data from BuzzRx shows that one in nine travelers have had to cancel their trip after having medicine confiscated at the airport, and one in six have been able to replace their meds but had to pay full price for the prescription.

More than 50% of the respondents to BuzzRx’s survey said having their medicine increased their stress and anxiety around a trip, and 18% said it forced them to cancel some trip activities.

Anxiety medication was the most common type to be confiscated, followed by sleep aids and over-the-counter remedies.

Rodriguez said travelers should reach out to their doctor to see about getting confiscated medicine replaced, or consider seeking help from a consulate or embassy if the issue happens abroad.

Zach Wichter is a travel reporter based in New York. You can reach him at [email protected]

Everything you need to know about traveling with medication

While getting to travel is an incredible opportunity, it doesn't always come without some annoyances.

In addition to ongoing COVID-19 testing requirements and restrictions, you also have to deal with packing — in particular, how to pack medication you might need on the trip. After all, the last thing you want during a getaway is to run out of prescription medication (especially if you're stuck someplace due to a positive coronavirus result) or come down with a nasty head cold without access to over-the-counter medications.

For more TPG news delivered each morning to your inbox, sign up for our daily newsletter .

That's why it's essential to know certain key details when hitting the road with medications in tow . To find out the best way to be prepared for your vacation, TPG spoke with Dr. Julian Klapowitz of Travel Medicine Consultations, who shared everything you need to know about traveling with medication.

Should I pack my medication in my carry-on bag?

The short answer is yes; that way, you don't risk losing essential medicine in your checked luggage. In fact, the U.S. Centers for Disease Control and Prevention specifically recommends carrying your prescription medication.

"If I give someone three months of malaria pills, I still tell people to put everything in their carry-on," said Klapowitz. "That way, it doesn't accidentally get lost. Plus, the luggage storage area of the airplane can be freezing. So, anything liquid — like insulin — may end up frozen."

How much medication am I allowed to bring?

Generally speaking, 30 days' worth of medication is acceptable pretty much everywhere. If it's more than that, a doctor needs to provide a note, and you should also have the original prescription, according to Klapowitz. Just allow for extra time at security if you have larger amounts of pills or liquid medicine that doesn't fall into traditional TSA guidelines.

When traveling internationally, the quantity issue really boils down to the types of medications allowed in your destination.

What if I'm traveling for an extended period?

The same answer from above pretty much applies here.

"If you're traveling for more than 30 days, try to have the medication you will need for the entirety of the trip," said Klapowitz. "But, again, those larger quantities will require a doctor's note and original prescriptions to prove the need to travel with that amount."

How do I get medication abroad?

If you don't have enough medicine to get you through an entire vacation or are stuck needing something abroad, there are ways to get medication. Interestingly, the U.S. is more strict regarding many medications than many other countries where you can purchase antibiotics, blood pressure medications and a variety of other pills over the counter.

But, in some destinations, counterfeit medications are a major problem.

"You should be fine to walk into a pharmacy or doctor's office in places like Western Europe and know it's safe," said Klapowitz. "If you're somewhere that's not as reliable, contact the nearest U.S. embassy or consulate. They should be able to get you in touch with reputable doctors and pharmacies."

Are there destinations that have medication restrictions?

Yes, some destinations do have medication restrictions. For example, Japan doesn't allow certain allergy and sinus medications, and types of inhalers are illegal. Plus, travelers to the United Arab Emirates have ended up in prison because the country has strict narcotics laws.

"Before traveling internationally, check with the foreign embassy of your destination to make sure your medicines are allowed in that country," said Klapowitz. "If it is banned, talk with your doctor about possible alternatives. Or, if you plan to travel with it, be sure all medication is in the original bottle.

"You should also have a doctor's letter explaining the condition and need for the specific restricted medication and an original prescription," Klapowitz added. "Of course, it's not guaranteed you'll be allowed to keep it, but it certainly increases your chances."

Which medications are often restricted?

The most common banned substance is narcotics. "If somebody is thinking about taking codeine, Percocet, Vicodin or methadone, I usually advise to see if it's possible to travel abroad without them," said Klapowtiz.

"The same is true for some regulated psychotropic medications like Adderall and Ambien. But always do your research on the specific destination."

How can I travel with a restricted medication?

Unfortunately, sometimes the answer is that you just can't travel with restricted medication.

But, countries will have a variety of rules — i.e., allow 30-days' worth — so it's important to contact the embassy to see what's allowed. "

Again, if you plan to travel with a restricted medication, be sure you have the documentation to back it up, and everything is clearly labeled," said Klapowitz.

What if my medication is liquid?

If traveling domestically, liquids are allowed so long as they adhere to the TSA's 3.4-ounce rule and fit in a quart-sized bag.

The TSA will allow you to travel with more than that amount, but you must declare the liquid medications to TSA officers at security for inspection.

"The same is basically true for international destinations, so long as it's not a banned substance," said Klapowtiz. "Just be sure to have the original prescription and doctor's note, and leave time for extra security checks."

Can I bring syringes?

Usually, bringing sharp, pointy objects onto a plane isn't allowed. But, some medicines require the use of syringes or needles.

"If you have diabetes, for example, have the same documentation as you would for a restricted medication," said Klapowitz. "Unused syringes and needles are allowed when accompanied by the medication, prescription and doctor's note."

Are there medications I should always bring with me when I travel?

"I always recommend bringing Tylenol, Motrin or Advil for pain and fever, and Imodium for mild diarrhea," said Klapowitz.

"You should also consider taking an antacid if the local diet doesn't agree with you. Then, for anybody who gets motions sickness , pack Dramamine."

In addition to those standard medications, Klapowitz suggested bringing any OTC medications you commonly use.

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I am traveling with medication, are there any requirements I should be aware of?

All passenger items must undergo security screening. It is recommended that medication be clearly labeled to facilitate the screening process.

You may bring medically necessary liquids, medications and creams in excess of 3.4 ounces or 100 milliliters in your carry-on bag. Remove them from your carry-on bag to be screened separately from the rest of your belongings.

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Traveling Abroad with Medicine

Many international travelers carry medicines with them to treat acute or chronic health problems. However, each country has its own laws related to medicines. Medicines that are commonly prescribed or available over the counter in the United States might be unlicensed or considered controlled substances in other countries. While rules vary by country, there can be serious consequences if you violate the laws at your destination. The consequences may include:

• Authorities taking away your medicine
• Penalties, including jail or prison time

Before Travel

Check with your destination’s  embassy and embassies of countries that you have layovers in to make sure your medicines are permitted.

• Many countries allow a 30-day supply of certain medicines, but also require the traveler to carry a prescription or a medical certificate from their health care provider.
• If your medicine is not allowed at your destination, talk with your health care provider about alternatives and have them write a letter describing your condition and the treatment plan.
• You may also want to check the  International Narcotics Control Board  website that provides general information about narcotics and controlled substances, for countries that have information available, for travelers.

Check CDC’s destination pages for travel health information . Check CDC’s webpage for your destination to see what vaccines or medicines you may need and what diseases or health risks are a concern at your destination.

Make an appointment with your healthcare provider or a travel health specialist  that takes place at least one month before you leave. They can help you get destination-specific vaccines, medicines, and information. Discussing your health concerns, itinerary, and planned activities with your provider allows them to give more specific advice and recommendations.

• If you plan to be gone for more than 30 days, talk to your health care provider about how you can get enough medicine for your trip. Some insurance companies will only pay for a 30-day supply at a time.
• If you are a traveling to a different time zone, ask your health care provider about any changes to taking your medicine. Medicines should be taken according to the time since your last dose, not the local time of day.
• Find out how to safely store your medicine while traveling and check whether it needs refrigeration. Keep in mind that extreme temperatures can reduce the effectiveness of many medicines.

Prepare a  travel health kit   with items you may need, especially those items that may be difficult to find at your destination. Include your prescription and over-the-counter medicines in your travel health kit and take enough to last your entire trip, plus extra in case of travel delays. Pack medications in a carry on in case your luggage is lost or delayed.

• Keep medicines in their original, labeled containers. Ensure that they are clearly labeled with your full name, health care provider’s name, generic and brand name, and exact dosage.
• Bring copies of all written prescriptions, including the generic names for medicines. Leave a copy of your prescriptions at home with a friend or relative in case you lose your copy or need an emergency refill.
• Ask your prescribing health care provider for a note if you use controlled substances, or injectable medicines, such as EpiPens and insulin.

Buying Medicine Abroad

Counterfeit drugs  are common in some countries, so only use medicine you bring from home and make sure to pack enough for the duration of your trip, plus extra in case of travel delays. If you must buy drugs during your trip in an emergency, see CDC’s Counterfeit Drugs page.

More Information

• CDC Yellow Book: Avoiding Poorly Regulated Medicines
• Travel Smartly with Prescription Medications (US Department of State)
• Traveling with Prescription Medications (US Food and Drug Administration)

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Understanding Benzodiazepines and How They Work

• How They Work
• Side Effects
• Drug Interactions

Advantages vs. Disadvantages

• Alternatives

Benzodiazepines are a class of drugs (commonly referred to as “benzos”) prescribed to treat anxiety, panic disorder , seizures, insomnia, and alcohol withdrawal . They may also be used along with anesthesia during surgery.

Benzodiazepines work by targeting and binding to the gamma-aminobutyric acid (GABA) neurotransmitter in the brain. This slows the central nervous system (CNS), resulting in a calming, sedating effect.

This article will cover how benzodiazepines work, their side effects and safe use, their possible drug interactions, and alternative medications.

Getty Images / Niall Carson - PA Images  / Contributor

What Are Benzodiazepines Used For?

Approved indications for benzodiazepine use in adults include:

• Anxiety disorders, including generalized anxiety, short-term anxiety, and preoperative anxiety
• Panic disorder
• Status epilepticus or seizures in adults
• Alcohol withdrawal

Benzodiazepines also have a fair number of off-label uses. When a healthcare provider uses a drug approved by the Food and Drug Administration (FDA) for an unapproved use, that use is considered off-label.

Providers are generally able to use their medical expertise to prescribe FDA-approved drugs for unapproved uses as long as they judge that the drug is medically appropriate for you.

Examples of these uses with benzodiazepines include:

• Sedation in the intensive care unit (ICU)
• Short-term treatment of spasticity (muscle stiffness or rigidness) in children with cerebral palsy
• Use alongside antipsychotics, mood stabilizers, and antidepressants in treating psychotic disorder, bipolar disorder, and other mood disorders
• Chemotherapy-associated anticipatory nausea and vomiting
• Restless legs syndrome (condition causing a strong urge to move the legs)
• Tardive dyskinesia (side effect of medications causing involuntary repetitive movements)
• REM (rapid eye movement) sleep behavior disorder (sleep disorder causing physical and vocal acting out during REM sleep)

How Do Benzodiazepines Work?

Benzodiazepines, as a class, work on a certain type of receptor found throughout your brain and spinal cord, which make up the central nervous system .

This receptor is a protein called gamma-aminobutyric acid type A (GABA-A) receptor. Benzodiazepine drug molecules mimic the naturally occurring neurotransmitter GABA and bind to this receptor. This allows chloride ions to enter the neuron cells, which results in CNS depression. Outward signs of this include calmness, sleepiness, or drowsiness.

How quickly benzodiazepines begin to work depends on which specific drug you’re taking and how you’re taking it. Taken orally, most benzodiazepines are well absorbed. Some of the fastest-acting drugs in this class are:

• Valium (alprazolam)
• Halcion (triazolam)
• Xanax (diazepam)

Intravenous (IV) injection results in rapid onset of effects. Midazolam, in particular, is one of the most lipophilic benzodiazepines, meaning it rapidly crosses the blood-brain barrier (to enter your CNS).

Why Benzodiazepines Work

Benzodiazepines target and bind to a receptor in the brain and spinal cord called GABA-A by mimicking naturally occurring GABA. This is what causes the effects of CNS depression, like sleepiness and calmness.

These effects help relieve the symptoms of certain conditions it's used for, such as anxiety and panic disorder, and are why it is sometimes used for sedation.

Examples of Benzodiazepines

Benzodiazepines are often classified by their onset of action—how quickly they begin to work after you take them. This also affects their most common uses.

For example, midazolam is given by injection and often used alongside anesthesia medications because it works quickly to cause sleepiness. It is also commonly used as a nasal spray for both anesthesia and seizures.

In comparison, Klonopin (clonazepam) is taken by mouth and used more often for panic disorder and seizure prevention because it lasts longer and is usually taken two times per day.

Most Commonly Prescribed Benzodiazepines

The most commonly prescribed benzodiazepines are:

What Are the Side Effects of Benzodiazepines?

Side effects of benzodiazepines are somewhat common. For example, the following side effects have occurred in greater than or equal to 1% of people taking Xanax during clinical trials:

• Akathisia (restlessness)
• Dermatitis (skin irritation or rash)
• Hypotension (low blood pressure)
• Increased salivation
• Light-headedness

Another commonly used benzodiazepine, Valium, has been associated with the following side effects:

• Blurred vision
• Constipation
• Slurred speech

Some more serious warnings exist for the benzodiazepine drug class as a whole. These include:

• Abuse, misuse, and addiction
• Dependence and withdrawal
• Respiratory depression in those with impaired breathing

How to Take Benzodiazepines Safely

While effective for various medical uses, benzodiazepines can sometimes cause side effects. For this reason, it's important to take them exactly as instructed by a healthcare provider.

However, here are a few general tips for taking benzodiazepines safely:

• Start at a low dose and frequency, and have another discussion with your healthcare provider no more than two to four weeks after you begin taking benzodiazepines to reevaluate effectiveness, side effects, and risks.
• Be careful about mixing benzodiazepines with other depressant substances like alcohol and opioids.
• If you take benzodiazepines on a regular, scheduled basis for several weeks or longer, do not stop taking them abruptly, as they need to be tapered down slowly to avoid withdrawal symptoms such as insomnia, anxiety, or tremor.

Benzodiazepine Use in Older Adults

The American Geriatrics Society (AGS) lists benzodiazepines as a class of medications that should be avoided in people 65 and older. Nevertheless, they're still occasionally prescribed to this population.

Use of these drugs in older adults comes with risks of dependence, cognitive deficits (or impaired thinking), falls, and car accidents.

These risks are even greater if benzodiazepines are used in older people who have a history of falls or who are already receiving two or more other CNS drugs (such as opioids, muscle relaxants, sleeping pills, or barbiturates, among others).

In cases in which benzodiazepines are necessary in an older individual, the most favored options are known as the “LOT drugs” (lorazepam, oxazepam, and temazepam). This is because they are shorter-acting and do not have active metabolites, making them less likely to cause residual or longer-term side effects.

Even in this case, the lowest effective dose for the shortest possible period will prove to be the safest in older adults.

Drug Interactions to Watch Out For

If you take benzodiazepines, be aware of potential drug or substance interactions. This includes:

• Alcohol: Alcohol is another depressant that also mimics the GABA neurotransmitter and can have a combined sedative or respiratory depressant effect if mixed with benzodiazepines.
• Sedatives like barbiturates (phenobarbital, pentobarbital): These medications that also bind to the GABA receptor and have a depressant effect can be dangerous when mixed with benzodiazepines.
• Opioids (such as hydrocodone, oxycodone , morphine): Opioids also suppress respiratory function and slow down your central nervous system. Combining them with benzodiazepines has been shown repeatedly in research to increase the likelihood of emergency room visits and death from drug overdose.
• Certain drugs called UGT inducers (e.g., carbamazepine, phenobarbital, phenytoin, and rifampin): These may make some benzodiazepines (e.g., lorazepam and oxazepam) clear from your system more quickly, reducing their effectiveness.
• CYP3A4 inhibitors like Prozac (fluoxetine), Luvox (fluvoxamine), oral contraceptives, ketoconazole, grapefruit juice, and clarithromycin: These may disrupt the clearance of benzodiazepines from your body, resulting in buildup, heavier sedation and potential worsening of side effects. If you also take these medications, you may get the same effects from a lower dose of benzodiazepines.

Benzodiazepines have both advantages and disadvantages to their use. While effective, they can come with potentially serious side effects and require some precautions when taking them.

Effective at reducing anxiety

Helpful for sleep problems

Work well as muscle relaxants

Can treat and prevent epileptic seizures

Variety of options within the drug class with different onsets and durations of actions

Potential for misuse, abuse, and addiction

Has cognitive side effects, such as mental slowing and anterograde amnesia (difficulty forming new memories)

Can be habit-forming and difficult to taper down the dose in people who have taken them regularly for more than a few weeks

Not recommended for use in older people (65 and above) due to the increased risk of respiratory depression, excessive sedation, and cognitive effects

Alternatives to Benzodiazepines

Benzodiazepines are often prescribed for conditions like anxiety and insomnia, even though other treatments exist that show equal or better results with fewer risks and side effects.

A few alternatives to benzodiazepine therapy are:

• Psychotherapy and behavior modification (such as cognitive behavioral therapy , stimulus control, and sleep restriction) are the types of treatments that are recommended first-line for cases of anxiety and insomnia.
• Medications may be considered alongside psychotherapy for anxiety, but only serotonergic agents like selective serotonin reuptake inhibitors (SSRIs) are considered first-line medications.
• Vistaril (hydroxyzine) may be effective for anxiety and insomnia, as well as nausea and vomiting or allergies

Older adults are somewhat limited in options for safe medications due to the likelihood of side effects of many drugs worsening with age.

However, the AGS considers antidepressants Silenor (doxepin) and Remeron (mirtazapine) as good and safe options for treating insomnia in older people.

Benzodiazepines are a powerful medication class with a wide variety of indications and off-label uses, such as anxiety disorders, epileptic seizures, and insomnia, and for initiating anesthesia.

While effective for these purposes, benzodiazepines come with several important risks to consider. They are associated with dependence, misuse and abuse, cognitive impairments, and increased likelihood of severe side effects, particularly when combined with other depressant substances like opioids or alcohol.

The safest way to take benzodiazepines is on an as-needed basis rather than scheduled, at the lowest effective dose possible, and ideally for only a short period.

Speak with your healthcare provider about first trying safer, evidence-based alternatives such as cognitive behavioral therapy and other medications like antidepressants.

Dubovsky SL, Marshall D. Benzodiazepines remain important therapeutic options in psychiatric practice . Psychother Psychosom . 2022;91(5):307-334. doi:10.1159/000524400

Edinoff AN, Nix CA, Hollier J, et al. Benzodiazepines: uses, dangers, and clinical considerations . Neurol Int . 2021;13(4):594-607. doi:10.3390/neurolint13040059

Jacobi J, Fraser GL, Coursin DB, et al. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult . Crit Care Med . 2002;30(1):119-41. doi:10.1097/00003246-200201000-00020

Chung CY, Chen CL, Wong AM. Pharmacotherapy of spasticity in children with cerebral palsy . J Formos Med Assoc . 2011;110(4):215-222. doi:10.1016/S0929-6646(11)60033-8

Perwitasari DA, Gelderblom H, Atthobari J, et al. Anti-emetic drugs in oncology: pharmacology and individualization by pharmacogenetics . Int J Clin Pharm . 2011;33(1):33-43. doi:10.1007/s11096-010-9454-1

Carlos K, Prado GF, Teixeira CD, et al. Benzodiazepines for restless legs syndrome . Cochrane Database Syst Rev . 2017;3(3):CD006939. doi:10.1002/14651858.CD006939.pub2

Bergman H, Bhoopathi PS, Soares-Weiser K. Benzodiazepines for antipsychotic-induced tardive dyskinesia . Cochrane Database Syst Rev . 2018;1(1):CD000205. doi:10.1002/14651858.CD000205.pub3

Jiménez-Jiménez FJ, Alonso-Navarro H, García-Martín E, Agúndez JAG. Current treatment options for REM sleep behaviour disorder . J Pers Med . 2021;11(11):1204. doi:10.3390/jpm11111204

Prommer E. Midazolam: an essential palliative care drug . Palliat Care Soc Pract . 2020;14:2632352419895527. doi: 10.1177/2632352419895527

National Institutes of Health. DailyMed. Label: midazolam hydrochloride injection, solution .

National Institutes of Health. DailyMed. Label: Nayzilam midazolam spray .

National Institutes of Health. DailyMed. Label: Klonopin clonazepam tablet .

National Institutes of Health. DailyMed. Label: Halcion triazolam tablet .

National Institutes of Health. DailyMed. Label: Restoril temazepam capsule .

National Institutes of Health. DailyMed. Label: Xanax alprazolam tablet.

National Institutes of Health. DailyMed. Label: Ativan lorazepam tablet .

National Institutes of Health. DailyMed. Label Chlordiazepoxide hydrochloride capsule .

National Institutes of Health. DailyMed. Label: Valium diazepam tablet .

National Institutes of Health. DailyMed. Label: Valtoco diazepam spray .

National Institutes of Health. DailyMed. Label: diazepam injection, solution .

Kroll DS, Nieva HR, Barsky AJ, Linder JA. Benzodiazepines are prescribed more frequently to patients already at risk for benzodiazepine-related adverse events in primary care . J Gen Intern Med . 2016;31(9):1027-1034. doi:10.1007/s11606-016-3740-0

Markota M, Rummans TA, Bostwick JM, Lapid MI. Benzodiazepine use in older adults: dangers, management, and alternative therapies . Mayo Clin Proc . 2016;91(11):1632-1639. doi:10.1016/j.mayocp.2016.07.024

National Institutes of Health. Benzodiazepines and opioids .

Baldwin DS, Aitchison K, Bateson A, et al. Benzodiazepines: risks and benefits. a reconsideration . J Psychopharmacol . 2013;27(11):967-971.

Guina J, Merrill B. Benzodiazepines I: upping the care on downers: the evidence of risks, benefits and alternatives . J Clin Med . 2018;7(2):17. doi:10.3390/jcm7020017

By Sara Hoffman, PharmD Hoffman is a Kansas-based clinical pharmacist with experience working in hospitals, specialty clinics, and community pharmacies.

That medication you’re taking? It may not be allowed in another country

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Your medications are such an ingrained part of your life that you hardly give them a second thought. But when you’re traveling abroad, you must give them a second and even a third thought, not only because you must maintain your routine but also because you need to stay out of trouble with the authorities. You want to spend time in the country, not in the clink.

A reader brought this to my attention by asking a question about Adderall, a medication often prescribed for attention-deficit hyperactivity disorder. She was traveling to Asia and had learned that the commonly prescribed medication is not allowed in her destination.

Adderall is a stimulant, Dr. Glenn Hardesty, an emergency room physician with Texas Health Plano, reminded me. But, he said, it is technically different, although customs or other officials and a country’s law may not see it that way.

That’s just one of the medications that might set off alarm bells. Another: Sudafed, which can be used in the production of methamphetamine.

But mostly, Hardesty said, “It’s the narcotics and psychotropics that cause concern, and it’s hard to know what countries will have problems [with their import] and which will not.”

Therein lies the problem. There is no central place to find out which country will allow Xanax, Ambien, Valium or other drugs — and which will not.

The International Narcotics Control Board , which describes itself as an “independent, quasi-judicial expert body for the implementation of the United Nations international drug control conventions,” can be a starting point. It has information on countries’ policies, but some of that information is ancient or incomplete, and some countries are absent.

What’s a traveler to do? Here are some tips from professionals.

♦ Routine medications such as those for blood pressure generally aren’t a problem, Hardesty said. But, he added, “As a general rule, medications that are considered problematic here probably will be problematic elsewhere.” Those are the ones, he said, that you can’t walk into a drugstore and buy off the shelf.

♦ Call the embassy or consulate of the country you are planning to visit and ask specifically about that drug. Find out also whether there is a limit to the amount you can bring into the country, said Victoria Sowards, director of wellness and nursing resources for Passport Health , which offers immunizations and counseling to people who travel internationally. Too much of a medication may make it appear as though you are trafficking, Hardesty said.

♦ Carry with you a letter from your doctor that gives the name of the medication — brand as well as generic names — the dosage and why it is prescribed. If you’re carrying syringes for insulin injections, a letter explaining why you have them may be helpful.

♦ Having a copy of your prescription with you is also a wise move, said staff of the International Assn. for Medical Assistance for Travelers , a nonprofit organization focused on traveler health. You may not be able to fill that prescription, but the organization can provide information about local doctors who may be able to write you a prescription.

♦ If your medication could raise eyebrows, talk to your doctor to see whether there’s another medication that can help. In no case should you go without that medication, said IAMAT staff, who noted that the nonprofit can help you find a doctor at your destination.

“We maintain a list of reputable English-speaking doctors around the world,” its email said. “Our members can contact a doctor before or during their trip to confirm availability of a medication or make an appointment.”

♦ When you pack your medications, make sure they are in their original bottles with the patient’s name on the bottle, Sowards said. And you should carry only your own. “Mrs. Jones should not be carrying Mr. Jones’ prescriptions,” she said.

♦ When you pack those medications, make sure they are in your carry-on bag in case your checked bag goes astray. Even though you won’t let your carry-on bag out of your control, affix a luggage tag just in case.

One final thought: If you have a chronic condition, Sowards said, consider medical evacuation insurance. Medications and evacuation insurance can keep you going in the right direction.

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Can I Bring Xanax Back from Mexico? A Comprehensive Guide

Xanax is a popular prescription drug in the United States that is used to treat anxiety and panic disorders. However, the rising costs of medication have caused many Americans to turn to Mexico for more affordable options. This has raised the question: Can you bring Xanax back from Mexico to the USA?

If you are considering bringing Xanax back from Mexico, it’s essential to understand the legal framework, the FDA rules, and the customs and border protection regulations involved in this process. This comprehensive guide will provide you with step-by-step instructions on how to obtain a prescription in Mexico, buy Xanax from a Mexican pharmacy, and cross the border legally with your medication.

While there are benefits to bringing Xanax back from Mexico, there are also potential safety and quality concerns that you should be aware of. We will discuss the risks and benefits of bringing Xanax back from Mexico to help you make an informed choice.

So, if you’re wondering whether you can bring Xanax back from Mexico and how to do it legally, then keep reading for a comprehensive guide on all you need to know.

Table of Contents

The Legal Framework for Bringing Xanax Back from Mexico to the USA

If you plan to buy Xanax, a prescription medication, from a Mexican pharmacy, it is important to understand the legal restrictions for bringing the medication back to the USA. The Federal Drug Administration or FDA regulates the drugs sold and distributed in the US. Therefore, any prescription medication purchased outside of the US must comply with the FDA standards as well.

The FDA Rules You Should Know

According to the FDA, controlled medication such as Xanax, falls under the category of scheduled substances and requires a prescription in the US. Furthermore, importing any controlled substance without a valid prescription or an import license is illegal and can result in arrest or seizure of the medication. Similarly, any medication that lacks FDA approval or violates safety standards is prohibited from import.

If you are traveling with Xanax for personal use, the FDA allows three months’ worth of supply for a valid prescription. However, for any quantities above that, you must prove that the medication is solely for personal use, and presenting the prescription and a doctor’s note may help avoid confiscation at the customs.

The Customs and Border Protection Regulations to Consider

While the FDA sets the guidelines on the medication’s legality, the US Customs and Border Protection or CBP has additional regulations that must be followed. When crossing the border, you must declare all your medication , including the ones purchased in Mexico. The medication must be in their original packaging and match the prescription’s label .

Also, bear in mind that the CBP officers have the power to search your belongings , including your medication and call the authorities if they suspect illegal activity. Therefore, it is advisable to carry your prescriptions, medical IDs, and doctor’s contact information to avoid such situations.

In conclusion, purchasing prescription medication such as Xanax in Mexico can be cheaper but involves complying with the FDA and CBP regulations. By following the legal framework, you can avoid legal trouble and medication confiscation while ensuring your health’s safety.

Bringing Xanax from Mexico: A Step-by-Step Guide

Getting a prescription in mexico.

Many Americans travel to Mexico to purchase prescription drugs at a lower cost than in the United States. However, it is important to note that not all medications are available without a prescription . To obtain a prescription, visit a Mexican doctor or clinic and provide your medical history, including any current medications . The doctor will determine if Xanax or any other medication is necessary and prescribe it if appropriate.

Buying Xanax from a Mexican Pharmacy

Once you have a prescription, you can purchase Xanax from a Mexican pharmacy. It is recommended to research the pharmacy beforehand to ensure it is licensed and reputable . Be sure to purchase the medication in the original packaging and follow your doctor’s instructions for dosing and use.

How to Cross the Border Legally with Xanax

When crossing the border from Mexico to the United States, it is important to declare any prescription medications, including Xanax . You may be asked for identification, and carrying a copy of your prescription can help verify the legitimacy of the medication . The limit for personal use of medication allowed across the border is a three-month supply , and the medication must be in its original packaging .

In summary, it is possible to bring Xanax from Mexico to the United States legally with a prescription. However, it is important to research the pharmacy, obtain a prescription from a licensed Mexican doctor, and declare the medication when crossing the border . Following these steps can ensure a safe and legal process for obtaining Xanax from Mexico.

The Risks and Benefits of Bringing Xanax Back from Mexico

Xanax, or Alprazolam, is a prescription medication used to treat anxiety and panic disorders. It is one of the most commonly prescribed medications in the United States. Due to the high cost of prescription medications in the United States, many individuals have started to look for cheaper options in other countries, including Mexico.

The Safety and Quality Concerns of Buying Xanax in Mexico

While it may seem like a good idea to purchase prescription medication in Mexico, there are serious safety and quality concerns that should be taken into consideration. Not all pharmacies in Mexico are licensed, and some may sell counterfeit medication that could be harmful. It is important to do research and only purchase medication from reputable pharmacies .

In Mexico, prescription medication is regulated by the Mexican government to ensure that it meets international quality standards. However, there have been cases of counterfeit medication being sold in Mexico, which can pose serious health risks to those who take it.

Another concern when purchasing medication in Mexico is that it may not be stored or transported properly, which can also affect its quality. Medications should be stored at the recommended temperatures and kept in their original packaging to ensure their effectiveness.

The Cost-Benefit Analysis of Bringing Xanax from Mexico

The cost of prescription medication in Mexico is often much lower than in the United States, which may be tempting for those looking to save money. However, there are additional costs to consider, such as travel expenses and potential health risks.

Bringing prescription medication back from Mexico is legal, as long as it is for personal use and not for resale. The amount of medication that can be brought back is limited to a three-month supply, and the medication must be in its original packaging .

It is important to consult with a healthcare professional before taking any medication, even if it has been prescribed in the past. They can provide guidance on dosage, potential side effects, and interactions with other medications.

In conclusion, while purchasing prescription medication in Mexico may be a cost-effective option, there are serious safety and quality concerns to consider. It is important to do research and only purchase medication from reputable pharmacies. It is also important to consult with a healthcare professional before taking any medication, even if it has been prescribed in the past.

Table 1: Comparison of Xanax Prices in Mexico and the US

List 1: tips for purchasing prescription medication in mexico.

• Research pharmacies before making a purchase
• Only purchase medication from licensed pharmacies
• Be aware of counterfeit medication
• Ensure medication is stored and transported properly
• Consult with a healthcare professional before taking any medication

In conclusion, bringing Xanax back from Mexico to the USA is possible if you follow the necessary legal requirements. Knowing the guidelines set by the FDA and Customs and Border Protection is crucial to avoid any legal issues. Additionally, obtaining a prescription from a reputable Mexican pharmacy and crossing the border legally will help mitigate risks associated with the safety and quality of the medication. However, before making any decisions, it’s important to weigh the cost-benefit analysis. To learn more about navigating the legal regulations and obtaining quality medication, check out other articles on my blog, I Can Find It Out.

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I’m Ethan Query, a seasoned problem-solver with an endless curiosity. With years of experience in various fields, my mission is to help you navigate through life’s ‘Can I?’ questions, no matter how big or small

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Traveling Europe with Prescription Drugs

We had originally planned to bring our prescriptions in a weekly pill organizer and leave the bottles (10) at home but I read that you need to travel with them in the original prescription containers. Another friend that travels frequently to Europe just takes them in an organizer and has no problems. Any suggestions?

Husband and I have been traveling with them in zip lock bags or pill a day containerd for years and never had an issue. Some folks print off copies of their prescriptions to take along but we never have

We have been using a pill organizer for years. I also bring extra labeled in a zip lock bag. We both only have a couple of meds to take. We also bring a pharmacy print out of our meds. I also take a screenshot to have on my phone. Never had a problem.

I don’t have a recommendation as to how to handle this but I will relate the situation that I faced in March of 2020.

I had only brought with me enough medication in pill organizers to cover me for just a few days beyond my scheduled trip when the U.S. closed its borders due to the pandemic. I was in Morocco and was faced with an extended stay. Well off to the pharmacy I went with essentially nothing (but the pills on hand and my head knowledge of what they were) to try and obtain more.

Having at least a copy of the prescriptions (i.e. labels from the bottles) would have made the process easier. I still use the pill organizers but now I carry extras in the original containers too.

As long as you are not carrying narcotics or any schedule controlled substances (example: Xanax), you should be fine with whatever organizational system you come up with. I just used small snack size baggies with the days meds, then all of those go in a bigger baggie, they can just be stuffed wherever and are small. That was the system that took up the least amount of space, I could pretty much just stuff them in my little side pocket inside my suitcase. A Note: if you are taking a flight that would correspond with the normal time you take your meds, make sure to pack that single dose in your carry on.

I, too, use organizers and snack baggies for my daily pills. I also print off my medication list from my healthplan which tells dosage, etc. and since most are generic I don't have to worry about a script that only has a brand name.

Do be aware that the advice you are getting is more or less what I did advice. You would be hard pressed to find a source, government or otherwise that will suggest its a good idea to bring your meds in anything but the original prescription bottles.

We put our meds in ziplock bags with an extra Rx label attached. In addition, we carry a copy of the data sheet that comes with the meds just as a back up to prove what they are. We've traveled to many countries that way and never had a problem.

I take the original bottles and plenty extra in case the unforeseen happens an I am unable to return home for a few weeks.

I keep them in a zipped travel bag I got at REI.

Always travel with meds in their original labeled plastic containers. Doesn’t weigh much and its the last thing I pack.

I keep a list of the meds on my iphone in the notes application. Also have a printed copy that goes into my travel folder.

Never had a problem.

I use organizers and have a photo of the bottles on my phone.

Along with all the pills in baggies, I print out our medication lists from our doctor’s website.

its not a good idea to bring your meds in anything but the original prescription bottles.

Not every country gives medication in prescription bottles. Some get blister packs. Others get pill envelopes. Etc, etc, etc.

Not every country gives medication in prescription bottles. Some get blister packs. Others get pill envelopes. Etc, etc, etc

Since you are being literal, perhaps we could just amend the statement to the 'original container as dispensed'. But I believe the original statement is what appears (paraphrased) in the advice given by the State dept. And the Canada govt travel site. European countries, for the most part don't seem too concerned about meds for personal use. But show up with a baggie full of self labeled pills in some other countries, and you could absolutely count on a lengthy conversation with a government officer.

A Note: if you are taking a flight that would correspond with the normal time you take your meds, make sure to pack that single dose in your carry on

I also wanted to comment on this, from Letizia. ALL of your meds should be in your carry on or your personal item when flying. You should NEVER put prescription meds in your checked bags, in case they are delayed or lost.

I gave the answer i gave because I am not prepared to be personally responsible for the results of any other answer. I carry 6 meds including one not approved for use in the EU and one that requires carrying syringes. What do I do? Not material to the question.

CJean- I agree one of the things that stays with you at all times are your meds BUT do you really want to be digging in your carry on for your pills or have the one single dose needed inflight conveniently in one baggie that is easily accessible? I just pack the one dose of X number of pills separate from my main stash, in the front pocket of my carry on.

I take pictures of the original bottles and keep on my phone if using a pill a day organizer. Never had issues at all anyhow. Thousands of people travel daily with medications. Even a 90 supply doesn't raise an eyebrow.

Most of our Rx's are 90 day supplies in unnecessarily large containers with way too much empty space. It seems ludicrous carrying these "original" bottles especially now that more space is also needed for test kits, masks, etc. My partner and I have never taken these original containers with us aside from my ambien....and even that is has gone to 90 day supplies in bottles that have too much wasted space. We've tried getting 30 day supplies for travel with somewhat smaller bottles but still way too much wasted empty space. The improvement was minimal and didn't justify losing the bulk 90 day savings. I suppose people could get different packaging options outside their paid plans if they are willing to pay for it.

(EDIT) A paper copy of the prescription arrives with our mail orders. We take that along with us and also snap a pic of the bottle with it's associated paper. The doctor gets me a smaller ambien Rx at the local pharmacy and I don't mind taking that small bottle with me. The doctor has indicated which of our medicines cannot have missed dosages...only one can have a few missed days.

Depending totally one’s health situation and caregivers, talking to your prescribing doctors about your trip may surprise you. Some non-critical and lifestyle meds can take a two- to four-week vacation without complications or side effects. You also can probably get along just fine for a few weeks without a collection of OTC meds and feel-good supplements. To find out, wean yourself off of them for the month before you depart.

The reason they say bring your medications in your original container is because they want to see that prescription label.

I put many of my prescriptions into small ziploc bags writing the name of the prescription on the bag. I have a copy of the prescription label and my labels have a description of the pill.

In my last 3 trips what I have done is carry my prescriptions in separate baggies for the time that I will be traveling plus 10 more in case of COVID. I make a photo copy of the prescription labels (the pharmacy can print extras for you), scan the copy and email it to myself and my phone. Haven't had problems yet.

Does anyone use Rx blister packs when traveling? The Rx label is on the card. You can cut off the used rows as you go to reduce bulk. If you prefer a 7-day organizer, you could use a Sharpie to write the day of the week on the blister pack card. Just a thought.

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Traveling with xanax in checked baggage. - Air Travel Forum

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Traveling with xanax in checked baggage.

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This post has been removed at the author's request.

How risk averse are you?

If your luggage goes missing you have lost your pills ... there are no checks for drugs exiting the US so you can easily carry them onboard, at least you will know where they are. And unless you are taking a whole carton surely you'll have the room in your carry-on?

Double check if you can take them into whatever country you are going to ... that's the important thing.

'or its better for me to take it in the carry on?' Yes it is. Again if you plan to take an amount for personal use there aren't likely to be questions asked, but that depends on the countries in South America you plan to visit.

The standard advice for medication is always:

- Put it in the hand luggage (so it cannot get lost)

- Have the original or a copy of the prescription with you (and/or maybe a doctors letter).

- Leave the medication in its original packaging (identification)

- Travel only with the quantity needed (plus a bit of reserve)

- Check out the legal requirements of the country you are visiting and transiting through.

I wonder why the OP wants to put their medication in their checked luggage ?

As said already. its always advised to carry personal medication in your hand luggage

I would put them in a carry on or a briefcase in their original package along with a prescription just in case. Medications should not be put in checked in luggage.

Agreed. I know that my wife has taken some pills away in her checked baggage because she didn't think she would need them during the travel phase of a trip. I, on the other hand, am loaded with medication that I need to take at different times, so for me the pills I need will always be with me.

The Op has gone now, but I think this drug is only available via prescription, but I guess it may be prescribed on a use as and when basis.

This topic has been closed to new posts due to inactivity.

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Ministero della Salute

Medicinali stupefacenti e precursori di droghe

Travelling internationally with medicines containing controlled substances.

The National Law for travellers carrying, for personal use, medical preparations containing internationally controlled drugs is reported in the Decree of the Ministry of Health November 16, 2007:

• Ministero della Salute. Decreto 16 novembre 2007. Norme concernenti la detenzione ed il trasporto di medicinali stupefacenti o psicotropi da parte di cittadini che si recano all'estero e di cittadini in arrivo nel territorio italiano (G.U. Serie Generale, n. 278 del 29 novembre 2007)

The Decree provides all the information and the procedures that international travellers should follow, in order to permit the carrying of small quantities of medical preparations containing narcotic drugs and psychotropic substances for personal medical use.

There are two separate issues:

• travellers entering Italy
• travellers leaving Italy

1. Travellers entering Italy

International travellers who plan to visit Italy and carry for their medical use preparations containing internationally controlled drugs are required to hold one of the following documents to serve as evidence that medical preparations were lawfully obtained by the traveler in the Country of departure:

• Certificate issued by Health Authorities of the country of residence

These certifications, issued on the basis of a valid medical prescription , must  indicate the following information:

A. Country and place of issue (Country, place of issue, date of issue, period of validity max 30 days)

B. Prescribing physician (Last name, first name, address, number of licence)

C. Patient (Last name, first name, sex, place of birth, date of birth, home address, number of passport or of identity card, intended country of destination)

D. Prescribed medical preparation (Trade name of drug or its composition, dosage form, number of units (tablets, ampoules etc.), international name of the active substance, concentration of active substance, total quantity of active substance, duration of prescription in days, signature and stamp of prescribing physician)

E. Issuing authority (Official designation (name) of the authority, address, official seal of the authority, signature of responsible officer)

It must be issued by a general practitioner (GP) or a pediatrician endorsed by the Authorities of the country of residence (physician duly authorized to prescribe internationally controlled drugs).

The documents should be in the traveler's possession during the stay, and should be available on request for presentation to the authorities.

2. Travellers leaving Italy

To deal with situations in which patients travelling abroad are carrying with them small quantities of preparations containing substances under international control, they are required to hold the following document to serve as evidence that medical preparations were lawfully obtained by the traveller in the Country of departure:  

• Annex 1 This certificate is issued on the basis of a valid medical prescription identifying the patient and indicating the type and amount of preparations that he/she is permitted to carry.
• Other documents eventually required by the foreign country (*)

The documents should be in the traveller's possession during the stay, and should be available on request for presentation to the authorities.

For travellers carrying only one package of the medical preparation already mentioned or medicinal preparations listed in Annex n. 2 of the Decree of the Ministry of Health November 16, 2007, is requested only a valid prescription according to what is reported for medical preparation listed in the schedules of the National Decree 309/90.

This situation doesn’t undergo the procedure mentioned above. (*) For more information all the travellers are advices to check thoroughly the following websites:

• International Narcotics Control Board
• INCB - Travelling Internationally with Medicines Containing Controlled Substances
• Ministero degli affari esteri e della cooperazione internazionale

Data di ultimo aggiornamento 12 marzo 2024

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How Long Does Xanax Withdrawal Last?

• Signs and Symptoms
• Coping and Relief
• Long-Term Treatment

What is the most important information I should know about Xanax withdrawal?

• Suddenly stopping Xanax can lead to severe and dangerous withdrawal symptoms; never adjust your dose or quit taking Xanax without talking to your doctor first.
• Xanax withdrawal can occur even when medication is taken as prescribed, but treatments are available that can help.

Xanax (alprazolam) is a common anti-anxiety medication . Doctors prescribe it for patients struggling with insomnia and mental health issues such as excessive worry, panic attacks , and post-traumatic stress disorder (PTSD).

Xanax can help people who are in acute distress, but it is not intended for long-term use. The long-term use of benzodiazepines like Xanax can potentially create problems with dependence and withdrawal .

If you or a loved one are struggling with substance use or addiction, contact the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-4357 for information on support and treatment facilities in your area.

For more mental health resources, see our National Helpline Database .

Overview of Xanax Withdrawal

Even if you only take Xanax for a period of several days, you may develop a physical dependence on the drug. This means that you will likely experience Xanax withdrawal, or the uncomfortable physical and mental symptoms of discontinuing the drug. The intensity of your symptoms depends on your dosage, or how much Xanax you've been taking and for how long.

Xanax withdrawal can also be medically serious. If you have been taking Xanax several times a day, then quitting is going to take time, patience, and determination . The only safe way to quit is to slowly taper down your dose under the direction of a doctor.

Quitting cold turkey can increase your risk of extreme and dangerous withdrawal symptoms, including delirium and grand mal seizures.

Delirium is a state that involves temporary, abrupt changes in cognition and behavior characterized by agitation and disorientation. A grand mal seizure (also known as a tonic-clonic seizure) involves violent muscle contractions and a loss of consciousness.

In 2017, doctors wrote nearly 45 million prescriptions for Xanax (alprazolam). Statistics suggest that one in 20 people in the U.S. fill a prescription for benzodiazepines each year.

Reckless prescribing practices have contributed to thousands of cases of dependence and misuse. Research shows that in 2018, an estimated 5.4 million people over the age of 12 misused prescription benzodiazepines like Xanax.

Xanax Withdrawal Symptoms & Signs

The signs and symptoms of Xanax withdrawal vary from person to person. Research indicates that roughly 40% of people taking benzodiazepines for more than six months will experience moderate to severe withdrawal symptoms. The remaining 60% can expect milder symptoms.

Hyperventilation

Muscle spasms

Racing pulse

Difficulty concentrating

Feelings of unreality

Hallucinations

Panic attacks

Restlessness

Xanax is a high-potency drug, which makes its withdrawal symptoms more intense than symptoms of withdrawal from other types of benzodiazepines such as Valium (diazepam).

What Does Xanax Rebound Mean?

Xanax's potency is linked with increased rebound effects . A rebound effect is the reoccurrence of a symptom after a person stops taking the medication that was treating it. For instance, someone taking Xanax for anxiety is likely to have a reoccurrence of their anxiety symptoms during withdrawal. This is sometimes called Xanax rebound anxiety.

Depending on the severity of your symptoms, the level of anxiety you experience during Xanax withdrawal may be more intense than what you experienced before taking Xanax. It is common to feel nervous, jumpy, and on-edge during your taper.

Many people experience irritability and agitation, which can cause problems at home, work, or school. You might be easily annoyed or short-tempered with family or friends. Insomnia, another symptom, can also contribute to these feelings of anxiety and agitation.

The symptoms of Xanax withdrawal typically appear within 8 to 12 hours of your last dose. If you fail to taper your dose, your withdrawal symptoms will grow increasingly intense. Withdrawal is generally at its worst on the second day, and improves by the fourth or fifth day; however, acute symptoms can last significantly longer.

• Early withdrawal symptoms : These symptoms usually occur within the first two days after your last dose. They usually include: headaches, insomnia, anxiety, restlessness, and/or panic attacks.
• Acute withdrawal symptoms : Symptoms tend to peak between the third day and the fifth or sixth day after your last dose. Additional symptoms may include: hallucinations, aggression, confusion, memory problems, high blood pressure, muscle aches, nausea, tremors, and more.
• Late withdrawal : After about a week of Xanax withdrawal, the physical symptoms may become more tolerable; however, other symptoms may occur after this period which includes Xanax cravings, anxiety or depression, insomnia, and/or suicidal ideation .

If you are having suicidal thoughts, contact the  National Suicide Prevention Lifeline  at  988  for support and assistance from a trained counselor. If you or a loved one are in immediate danger, call 911.

For more mental health resources, see our  National Helpline Database .

Protracted Withdrawal

Estimates suggest that about 10% to 25% of people who use benzodiazepines long term experience what’s known as protracted withdrawal.

Protracted withdrawal is a prolonged withdrawal experience marked by waves of mild psychological symptoms that come and go over the course of several months. Protracted Xanax withdrawal can last up to one year.

Factors That Affect Xanax Withdrawal

Xanax withdrawal isn't the same for everyone—there are unique factors that come into play. Be sure to consult with a healthcare professional if you have any mental health conditions including but not limited to:

• Panic disorder : One small study found that 15 out of 17 patients with panic disorder who were treated with alprazolam experienced panic attacks again (some at higher levels than pre-treatment) after discontinuing Xanax. These patients were tapered off of Xanax after four weeks, yet this rebound effect still occurred.
• Post-traumatic stress disorder (PTSD) : In another small study, all eight patients with PTSD who tapered off of Xanax after eight weeks experienced worsened anxiety, sleep disturbance, nightmares , irritability, rage, and homicidal ideation.
• Pregnancy : If you are pregnant, you are at an increased risk of Xanax withdrawal symptoms, including seizures.

Coping & Relief for Xanax Withdrawal

The best way to try to lessen the severity of your Xanax withdrawal symptoms is by slowly tapering down your dose of Xanax. Tapering means taking progressively smaller doses over the course of several weeks. It is not recommended to taper without the assistance and recommendations from your prescribing doctor.

Xanax is a short-acting drug, which means your body metabolizes it very quickly. Tapering Xanax is challenging because the amount of the drug in your system quickly goes up and down with each dose. To help you avoid these peaks and valleys, doctors often switch you from Xanax to a long-acting benzodiazepine such as Valium (diazepam) .

Switching from short-acting Xanax to its longer-acting cousin Valium will make it easier for you to quit. Once you are stabilized on a dose of diazepam, your prescribing doctor will help you slowly taper down a little bit at a time. This gives your body and mind the time to adjust to life without Xanax.

Alleviating Symptoms of Breakthrough Withdrawal

If you have breakthrough withdrawal symptoms when your dose is reduced, your prescribing doctor can pause or stretch out your taper. It’s up to you and the doctor to figure out the best tapering schedule for your individual needs. The doctor may also recommend one or more of the following treatment types:

• Cognitive behavioral therapy (though research is mixed on the effectiveness of CBT after three months)
• Herbal sleep aids such as valerian root and chamomile
• Mindfulness practice

Warnings About Xanax Withdrawal

Unlike many other withdrawal syndromes, benzodiazepine withdrawal can be complicated and, occasionally, life-threatening.

• Xanax withdrawal seizures may occur in some people—especially in those undergoing unsupervised and untreated withdrawal from Xanax.
• If you have been diagnosed with a serious mental illness in the past, such as a panic disorder , PTSD, bipolar disorder , or borderline personality disorder (BPD) , then great care should be taken when coming off of Xanax. In such cases, a doctor’s help will be invaluable. It can be difficult to predict which dormant symptoms, if any, may return when Xanax is removed from the equation.
• People with a history of complicated withdrawal syndromes and people with underlying health issues should also work closely with a doctor.
• Older adults and people with cognitive decline should also work closely with a doctor as there are unique risks for these groups.

If you plan to or have become pregnant, you will need to discuss your options with a doctor. Part of that conversation should include reviewing the risks and benefits of continuing versus tapering benzodiazepines during your pregnancy. Some people continue taking benzodiazepines throughout their pregnancy while others follow a dose tapering schedule.

If you are using Xanax without a prescription, you can still work with a doctor to taper down your dose. Start by visiting a primary care doctor or urgent care center and tell them that you are in or are planning to be in benzodiazepine withdrawal. If you don’t have insurance, visit a community health center.

If you are concerned about the risks involved in Xanax tapering for any reason, discuss these concerns with a doctor. You may be better suited for inpatient detoxification. While inpatient treatment is typically more expensive, it is covered by many insurance plans.

Long-Term Treatment for Xanax Withdrawal

When it comes to the long-term management of getting off benzodiazepines, there are two directions you can go. Research shows that most stable, healthy adults will achieve long-term abstinence after completing a taper.

The key to achieving this goal is to follow the tapering schedule to the very end. By the end of your taper, you might be cutting pills into halves or quarters.

Some people may be better suited for a harm reduction approach, in which the taper leads to a maintenance dose rather than abstinence.

Links & Resources

• American Society of Addiction Medicine (ASAM)
• Department of Health and Human Services (HHS)
• Substance Abuse and Mental Health Services Administration (SAMHSA)

Brett J, Murnion B. Management of benzodiazepine misuse and dependence .  Aust Prescr . 2015;38(5):152–155. doi:10.18773/austprescr.2015.055

U.S. Department of Justice, Drug Enforcement Administration, Drug & Chemical Evaluation Section. Benzodiazepines .

Bachhuber MA, Hennessy S, Cunningham CO, Starrels JL. Increasing benzodiazepine prescriptions and overdose mortality in the United States, 1996-2013 .  Am J Public Health . 2016;106(4):686-688. doi:10.2105/AJPH.2016.303061

Substance Abuse and Mental Health Services Administration. Key Substance Use and Mental Health Indicators in the United States: Results from the 2018 National Survey on Drug Use and Health .

Hood SD, Norman A, Hince DA, Melichar JK, Hulse GK. Benzodiazepine dependence and its treatment with low dose flumazenil .  Br J Clin Pharmacol . 2014;77(2):285–294. doi:10.1111/bcp.12023

Ait-Daoud N, Hamby AS, Sharma S, Blevins D. A review of alprazolam use, misuse, and withdrawal .  J Addict Med . 2018;12(1):4-10. doi:10.1097/ADM.0000000000000350

Edinoff AN, Nix CA, Hollier J, et al. Benzodiazepines: Uses, dangers, and clinical considerations . Neurology International. 2021;13(4):594-607. doi:10.3390/neurolint13040059

Páll A, Becs G, Erdei A, et al. Pseudopheochromocytoma induced by anxiolytic withdrawal .  Eur J Med Res . 2014;19(1):53. doi:10.1186/s40001-014-0053-9

Cato V, Holländare F, Nordenskjöld A, Sellin T. Association between benzodiazepines and suicide risk: a matched case-control study . BMC Psychiatry. 2019;19(1). doi:10.1186/s12888-019-2312-3

Darker CD, Sweeney BP, Barry JM, Farrell MF, Donnelly-Swift E. Psychosocial interventions for benzodiazepine harmful use, abuse or dependence . Cochrane Database Syst Rev . 2015;(5):CD009652. doi:10.1002/14651858.CD009652.pub2

Cardinali DP, Golombek DA, Rosenstein RE, Brusco LI, Vigo DE.  Assessing the efficacy of melatonin to curtail benzodiazepine/Z drug abuse .  Pharmacol Res.  2016;109:12–23. doi:10.1016/j.phrs.2015.08.016

Chakradhar T, Mondal S. Review on drug interactions of alprazolam on pharmacodynamic and pharmcokinetic actions . European J Biomed Pharm Sci . 2019;6(1):657-662.

Shyken JM, Babbar S, Babbar S, Forinash A. Benzodiazepines in pregnancy . Clin Obstet Gynecol . 2019;62(1):156-167. doi:10.1097/GRF.0000000000000417

American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. American Psychiatric Publishing.

Guina J, Merrill B. Benzodiazepines II: waking up on sedatives: providing optimal care when inheriting benzodiazepine prescriptions in transfer patients .  J Clin Med . 2018;7(2):20. doi:10.3390/jcm7020020

By Corinne O’Keefe Osborn Corinne Osborn is an award-winning health and wellness journalist with a background in substance abuse, sexual health, and psychology.

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Meth and Xanax pills seized, 2 arrested in small north Georgia town

Meth and Xanax seized, 2 arrested in small north Georgia town (Murray County Sheriff's Office)

CRANDALL, Ga. — Investigators seized meth and Xanax pills during a recent drug bust in north Georgia.

The Murray County Sheriff’s Office served a search warrant at a home on Peden Road in Crandall, Georgia.

Deputies seized approximately 11 ounces of methamphetamine, 83 grams of Xanax pills, one shotgun and several drug-related objects.

[DOWNLOAD: Free WSB-TV News app for alerts as news breaks ]

Priscilla Ridgeley, of Nashville, Tennessee, and Jason Brown, of Crandall, were arrested and charged with trafficking in methamphetamine, intent to distribute methamphetamine, possession of methamphetamine, possession of a firearm during the commission of a felony, intent to distribute a Schedule IV substance and possession of a Schedule IV substance.

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Meth and Xanax pills seized, 2 arrested in small north Georgia town

Investigators seized meth and Xanax pills during a recent drug bust in north Georgia.

The Murray County Sheriff’s Office served a search warrant at a home on Peden Road in Crandall, Georgia.

Deputies seized approximately 11 ounces of methamphetamine, 83 grams of Xanax pills, one shotgun and several drug-related objects.

[DOWNLOAD: Free WSB-TV News app for alerts as news breaks ]

Priscilla Ridgeley, of Nashville, Tennessee, and Jason Brown, of Crandall, were arrested and charged with trafficking in methamphetamine, intent to distribute methamphetamine, possession of methamphetamine, possession of a firearm during the commission of a felony, intent to distribute a Schedule IV substance and possession of a Schedule IV substance.

TRENDING STORIES:

Police take multiple protesters into custody on Emory University’s campus

Construction worker rescued after trench collapse at site of new Brookhaven city hall project

FDA, doctors warn about compounded Ozempic. What we found at metro weight loss clinics

[SIGN UP: WSB-TV Daily Headlines Newsletter ]

IN OTHER NEWS:

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